Effect of acute and chronic exercise on plasma matrix metalloproteinase and total antioxidant levels
نویسندگان
چکیده
The relationship between acute and chronic exercise and expression of matrix metalloproteinases (MMPs) in muscles is unknown. There happen some alterations in the oxidant-antioxidant balance due to exercise. This study aimed to investigate the levels of MMP-1, tissue inhibitors of metalloproteinases (TIMP-1), hyaluronic acid (HA), total antioxidant status (TAS), and total oxidant status (TOS) following acute and chronic exercising in rats. Twenty-six Wistar Albino male rats were divided in to three groups: control, acute, and chronic groups. In acute group, treadmill exercise was performed 3 days/wk, 10 min/day for 1 week. In chronic group, exercise performed 7 days/wk, 60 min/day for 4 weeks. At the end of the experiment, plasma MMP-1, TIMP-1, HA, TAS, and TOS levels were measured. In current study, the MMP-1, TIMP-1, HA, and TOS levels not observed statistically significant difference among all groups, but in chronic group, there was a significantly difference (P<0.05) between the control and experimental groups in terms of TAS and oxidative stress index (OSI) levels. TAS, TOS, and OSI levels were significantly different between control and chronic exercise group (P<0.01, P<0.05, and P<0.01, respectively). According to these results, we can say acute and chronic exercise does not effect on plasma MMP-1, TIMP-1, and HA levels.
منابع مشابه
Effect of Single Dose Administration of Methylsulfonylmethane on Oxidative Stress Following Acute Exhaustive Exercise
Methylsulfonylmethane (MSM) is a sulfur-containing compound commonly found in diet and known to reduce oxidative stress. This trial was conducted to determine whether single dose supplementation with MSM attenuates post-exercise oxidative stress in healthy untrained young men. Sixteen untrained men volunteered for this study. Participants were randomized in a double-blind placebo-controlled fas...
متن کاملEffect of Single Dose Administration of Methylsulfonylmethane on Oxidative Stress Following Acute Exhaustive Exercise
Methylsulfonylmethane (MSM) is a sulfur-containing compound commonly found in diet and known to reduce oxidative stress. This trial was conducted to determine whether single dose supplementation with MSM attenuates post-exercise oxidative stress in healthy untrained young men. Sixteen untrained men volunteered for this study. Participants were randomized in a double-blind placebo-controlled fas...
متن کاملThe effect of short-term colostrum supplementation on serum malondialdehyde levels and total antioxidant capacity due to acute resistance in healthy men
Background &aim:During intense exercise reactive species produce oxygen that results in cell damage. It seems that the use of antioxidant supplements reduces the oxidative stress caused by such exercises. Therefore the purpose of this study was to investigate the effect of short-term colostrum supplementation on serum malondialdehyde levels and total antioxidant capacity induced by acute resist...
متن کاملThe Antioxidant Role of Artichoke (Cynara scolymus L.) Extract Against Exhaustive Exercise-Induced Oxidative Stress in Young Athletes
Background: Strenuous acute exercise induces oxidative stress in the active muscles and circulation, However, consumption of products rich in antioxidants may potentially ameliorate these effects. Objective: The present investigation was conducted to determine the effect of Artichoke (Cynara scolymus L.) extract on oxidative stress and antioxidant defense after aerobic exercise in young athle...
متن کاملImpact of the Synchronization of portulaca oleracea and Aerobic Training on Levels of MMP2 and MMP9 and TIMP1 in Diabetic Women Type II
Background: Diabetes has the most important role in development of tissue damage, and by affecting intercellular matrices, may lead to structural and functional changes that ultimately cause failure of related tissue or organ. Exercise and herbal medicine can be effective in reducing organ failure. This study aims to assess the effect of aerobic training combined with consumption of portulaca o...
متن کامل